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Steve D Wilton Selected Research

RNA Precursors (Precursor, mRNA)

1/2021Analysis of Pathogenic Pseudoexons Reveals Novel Mechanisms Driving Cryptic Splicing.
10/2019Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides.
9/2017Inherited Retinal Disease Therapies Targeting Precursor Messenger Ribonucleic Acid.
10/2012Targeted exon skipping to address "leaky" mutations in the dystrophin gene.
4/2012Multiple exon skipping strategies to by-pass dystrophin mutations.
6/2010Dystrophin isoform induction in vivo by antisense-mediated alternative splicing.

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Steve D Wilton Research Topics

Disease

38Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
12/2020 - 06/2005
6Wasting Syndrome (Wasting Disease)
06/2020 - 01/2009
6Muscular Dystrophies (Muscular Dystrophy)
01/2019 - 02/2006
4Inborn Genetic Diseases (Disease, Hereditary)
01/2021 - 01/2017
4Spinal Muscular Atrophy (Progressive Muscular Atrophy)
10/2019 - 01/2013
3Disease Progression
11/2020 - 10/2019
3Progeria (Hutchinson Gilford Syndrome)
01/2014 - 01/2013
2Stargardt Disease
01/2022 - 01/2020
2Ataxia (Dyssynergia)
10/2021 - 10/2019
2Neoplasms (Cancer)
03/2021 - 03/2019
2Cystic Fibrosis (Mucoviscidosis)
01/2021 - 02/2018
2Parkinson Disease (Parkinson's Disease)
11/2020 - 10/2020
2Glycogen Storage Disease Type II (Pompe's Disease)
01/2020 - 01/2020
2Inflammation (Inflammations)
10/2019 - 11/2015
2Rare Diseases (Rare Disease)
01/2019 - 11/2018
2Muscular Atrophy (Muscle Atrophy)
11/2015 - 01/2011
1Retinal Dystrophies
01/2022
1Coronary Artery Disease (Coronary Atherosclerosis)
12/2021
1Dyslipidemias (Dyslipidemia)
12/2021
1Huntington Disease (Huntington's Disease)
10/2021
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
10/2021
1Mitochondrial Diseases (Mitochondrial Disease)
10/2021
1Nervous System Diseases (Neurological Disorders)
10/2021
1Carcinogenesis
03/2021
1Neuroblastoma
03/2021
1Retinitis Pigmentosa 11
01/2021
1Cognitive Dysfunction
11/2020
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020
1Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
10/2019
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
10/2019
1Multiple Sclerosis
10/2019
1Neoplasm Metastasis (Metastasis)
03/2019
1Lung Diseases (Lung Disease)
02/2018
1Retinal Diseases
09/2017
1Fibrosis (Cirrhosis)
01/2017
1Infections
01/2016
1Laminopathies
04/2014
1Muscular Diseases (Myopathy)
11/2013
1Inclusion Body Myositis
01/2013
1Asthma (Bronchial Asthma)
10/2010
1Respiratory Hypersensitivity
10/2010

Drug/Important Bio-Agent (IBA)

29DystrophinIBA
12/2020 - 02/2006
21Proteins (Proteins, Gene)FDA Link
12/2020 - 02/2006
12Antisense OligonucleotidesIBA
03/2021 - 06/2005
9MorpholinosIBA
12/2020 - 02/2006
6Protein Isoforms (Isoforms)IBA
03/2021 - 10/2011
6RNA Precursors (Precursor, mRNA)IBA
01/2021 - 06/2010
5Messenger RNA (mRNA)IBA
01/2021 - 01/2013
3OligonucleotidesIBA
01/2019 - 01/2017
3eteplirsenIBA
02/2018 - 10/2009
2polyglutamineIBA
10/2021 - 10/2019
2RNA (Ribonucleic Acid)IBA
03/2021 - 09/2017
2Pharmaceutical PreparationsIBA
01/2021 - 08/2011
2Peptides (Polypeptides)IBA
12/2020 - 10/2019
2Complement System Proteins (Complement)IBA
01/2020 - 11/2013
2AcidsIBA
01/2020 - 01/2020
2UtrophinIBA
01/2017 - 01/2011
2Nonsense Codon (Nonsense Mutation)IBA
01/2009 - 02/2006
1LipofuscinIBA
01/2022
1Lipoproteins (Lipoprotein)IBA
12/2021
1Long Noncoding RNAIBA
03/2021
1RNA Splicing FactorsIBA
01/2021
1MicroRNAs (MicroRNA)IBA
11/2020
1Nucleic AcidsIBA
11/2020
1parkin proteinIBA
10/2020
1Cell-Penetrating PeptidesIBA
06/2020
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2020
1GlucosidasesIBA
01/2020
1EnzymesIBA
01/2020
1NucleotidesIBA
01/2020
1alpha-Glucosidases (Acid Maltase)IBA
01/2020
1IntegrinsIBA
10/2019
1AngiopoietinsIBA
03/2019
1Epidermal Growth Factor (EGF)IBA
03/2019
1EndoglinIBA
03/2019
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2019
1Antisense RNA (Anti-Sense RNA)IBA
11/2018
1Surface-Active Agents (Surfactants)IBA
02/2018
1nusinersenIBA
02/2018
1Retinaldehyde (Retinal)IBA
09/2017
1InflammasomesIBA
01/2016
1Transcription Factors (Transcription Factor)IBA
11/2015
1Complement Membrane Attack Complex (Membrane Attack Complex)IBA
11/2013
1Signal Recognition ParticleIBA
11/2013
1AntibodiesIBA
11/2013
1HLA-DRB3 Chains (HLA DRB3)IBA
01/2013
1RNA Splice SitesIBA
01/2013
1Lamin Type A (Lamin A)IBA
01/2013
1UbiquitinIBA
01/2011
1Ligases (Synthetase)IBA
01/2011
1DNA (Deoxyribonucleic Acid)IBA
12/2010
1Biological ProductsIBA
10/2010
1Fibronectins (Fibronectin)IBA
10/2010
1Extracellular Matrix ProteinsIBA
10/2010
1Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
02/2009

Therapy/Procedure

17Therapeutics
10/2021 - 04/2006
2Intraperitoneal Injections
12/2020 - 01/2017
2Precision Medicine
11/2020 - 11/2018
1Radiotherapy
03/2019
1Drug Therapy (Chemotherapy)
03/2019